Table 3. Univariate analysis (Kaplan–Meier) on progression-free survival and overall survival of all patients according to patient age, clinical stage, nodal status and VEGF-A expression.

	Progression-free survival				Overall survival
Variable	Nb of patients	Nb of eventsa	Median survival time (mo)	P-value	Nb of patients	Nb of eventsa	Median survival time (mo)	P-value
Patient age				<1 × 10−3				0.030
<70 years	47	30	26.1		47	29	36.7
⩾70 years	7	7	6.0		7	6	8.2
Clinical stage				0.03				0.020
T1–T2	17	9	55.4		17	7	58.4
T3–T4	37	28	10.8		37	28	22.4
Nodal status				NS				0.050
N0	18	10	30.7		18	8	Not reached
N+	36	27	13.8		36	27	23.4
VEGF-A expression				0.001				0.003
<median	27	12	53.2		27	11	62.3
⩾Median	27	25	10.7		27	24	18.7

^aEvent for progression-free survival corresponds to the onset of local or distant recurrent disease. Event for overall survival corresponds to patient's death.

mo: months, Nb: number, NS: not significant; VEGF-A, Vascular endothelial growth factor A.