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. 2006 Apr 18;94(10):1395–1401. doi: 10.1038/sj.bjc.6603118

Table 7. Renal and liver function changes on treatment.

Laboratory test No. of evaluable pts Overall incidence (any grade) Grade 3 Grade 4
Serum creatinine 50 11 (22)
Bilirubin 51 3 (6) 1 (2) 1 (2)
SGOT/AST 48 12 (25) 1 (2)
SGPT/ALT 49 13 (27) 1 (2)
Alkaline phosphatase 49 25 (51) 5 (10)