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. 2006 Apr 25;94(10):1452–1459. doi: 10.1038/sj.bjc.6603110

Table 1. Clinical–pathological characteristics of patients in various molecular studies.

  Gene copy by qPCR (n=81) (%) Gene copy by FISH (n=59) (%) mRNA expression (n=130) (%) P- value
Age
 Mean 69.0 69.9 68.8 0.73
 Range (43.7–85.4) (43.7–85.4) (43.7–85.4)  
         
Gender
 Male 50 (61) 35 (59) 74 (57) 0.79
 Female 31 (39) 24 (41) 56 (43)  
         
Smoking history
 Smoker 59 (73) 41 (69) 92 (71) 0.99
 Nonsmoker 19 (23) 16 (27) 33 (25)  
 Unknown 3 (4) 2 (4) 5 (4)  
         
Pathological stage
 Stage I 52(64) 42 (71) 91 (70) 0.90
 Stage II 21 (26) 12 (20) 28 (22)  
 Stage III 8 (10) 5 (8) 11 (8)  
         
T stage
 T1 24 (30) 20 (34) 47 (36) 0.62
 T2 54 (66) 37 (63) 82 (63)  
 T3 3 (4) 2 (3) 1 (1)  
         
N stage
 N0 53 (65) 43 (73) 90 (69) 0.92
 N1 20 (25) 11 (19) 28 (22)  
 N2 8 (10) 5 (8) 12 (9)  
         
Histology
 ADC 40 (49) 32 (54) 83 (64) 0.03
 SQCC 37 (46) 26 (44) 38 (29)  
 Other 4 (5) 1 (2) 9 (7)  
         
Differentiation grade
 WD 20 (25) 16 (27) 33 (25) 0.98
 MD 30 (37) 19 (32) 44 (34)  
 PD 31 (38) 24 (41) 53 (41)  

The P-values were calculated using the χ2 test.

ADC=adenocarcinoma; SQCC=squamous cell carcinoma; WD=well differentiated; MD=moderately differentiated; PD=poorly differentiated; qPCR=quantitative polymerase chain reaction; FISH=fluorescence in situ hybridisation.