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. 2006 Apr 25;94(10):1452–1459. doi: 10.1038/sj.bjc.6603110

Table 5. Correlation between gene copy increases by qPCR and hTERT mRNA expression.

  Gene copy changes
 
  Nonamplified Amplified P-valuea
All 27 40  
 Normal expression 9b 4 0.03
 Overexpression 18 36  
       
Adenocarcinoma
 Normal expression 4 4 0.05
 Overexpression 4 24  
       
Squamous cell carcinoma
 Normal expression 4 0 0.12
 Overexpression 14 12  
a

P-values calculated using the two-sided Fisher's exact test.

b

One case was a large-cell carcinoma.

qPCR=quantitative polymerase chain reaction.