Table 5. Correlation between gene copy increases by qPCR and hTERT mRNA expression.
|
Gene copy changes
|
|||
|---|---|---|---|
| Nonamplified | Amplified | P-valuea | |
| All | 27 | 40 | |
| Normal expression | 9b | 4 | 0.03 |
| Overexpression | 18 | 36 | |
| Adenocarcinoma | |||
| Normal expression | 4 | 4 | 0.05 |
| Overexpression | 4 | 24 | |
| Squamous cell carcinoma | |||
| Normal expression | 4 | 0 | 0.12 |
| Overexpression | 14 | 12 | |
P-values calculated using the two-sided Fisher's exact test.
One case was a large-cell carcinoma.
qPCR=quantitative polymerase chain reaction.