Table 2. Decision table for the assessment of LVI or BVI based on the CD34/D2-40 staining profile of the vessel wall.

	D2-40−	D2-40+
CD34−	‘Overdiagnosis’ on HE	Lymph vessel ‘Picked up’ or ‘missed’ on HE
CD34 +	Blood vessel ‘Picked up’ or ‘missed’ on HE

BVI=blood vessel invasion; HE=haematoxylin–eosin; LVI=lymph vessel invasion.