Table 2. Univariate analysis on the association of the variables with the outcome measures.

	Progression-free survival			Overall survival
Variable	HR	95% CI	P-value	HR	95% CI	P-value
Age	1.03	1.01–1.05	0.01	1.03	1.01–1.05	0.001
Residual disease
Microscopic	Baseline			Baseline
⩽2 cm	2.50	1.42–4.40	0.001	2.06	1.20–3.54	0.01
⩾2 cm	7.07	3.94–12.67	<0.001	7.94	4.48–14.08	<0.001
Stage
I	Baseline			Baseline
II	2.14	0.92–4.95	0.08	2.27	1.03–5.04	0.04
III	3.98	2.16–7.34	<0.001	3.78	2.12–6.74	<0.001
IV	6.69	2.82–15.86	<0.001	5.33	2.33–12.15	<0.001
Histology
	Baseline			Baseline
Endometrioid
Clear cell	0.63	0.31–1.34	0.24	0.65	0.31–1.34	0.24
Mucinous	0.71	0.31–1.65	0.43	0.62	0.28–1.50	0.31
Serous	0.88	0.51–1.53	0.65	1.13	0.68–1.89	0.63
Others	1.25	0.54–2.89	0.60	1.35	0.59–3.11	0.48
Differentiation
Well	Baseline			Baseline
Moderate	1.42	0.73–2.73	0.30	1.32	0.72–2.43	0.37
Moderate–poor	0.77	0.62–5.04	0.29	1.80	0.69–4.69	0.23
Poor	1.92	0.95–3.87	0.07	1.59	0.81–3.12	0.17
Lymphatic count	1.01	0.99–1.03	0.30	1.01	0.99–1.03	0.41
Vascular count	0.99	0.95–1.02	0.53	0.98	0.95–1.02	0.34
TP
Stroma	1.00	0.81–1.24	0.96	1.11	0.90–1.38	0.33
0/1 vs 2 vs 3	1.01	0.76–1.35	0.94	1.14	0.85–1.51	0.38
0/1/2 vs 3	1.24	0.73–2.08	0.43	1.44	0.86–2.40	0.17
0/1 vs 2/3	0.86	0.53–1.41	0.56	1.06	0.65–1.74	0.81
Epithelium	1.21	0.73–2.04	0.46	1.07	0.63–1.80	0.80
VEGF
Epithelial	0.97	0.79–1.81	0.74	0.97	0.80–1.19	0.79
Macrophage	1.01	0.84–1.23	0.89	1.02	0.85–1.24	0.81
Stromal	1.01	0.80–1.28	0.94	0.99	0.78–1.26	0.94
Vascular	0.98	0.80–1.20	0.83	0.97	0.79–1.19	0.80
VEGF(0–3,4–7,8–12)	1.05	0.73–1.51	0.79	1.07	0.75–1.54	0.71

CI=confidence intervals; HR=hazards ratios; TP=thymidine phosphorylase; VEGF=vascular endothelial growth factor.

Age was analyzed as a continuous variable. Univariate analysis of TP and VEGF expression was performed by considering the trend in expression.