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. 2006 May 23;94(12):1833–1836. doi: 10.1038/sj.bjc.6603185

Table 2. Clinicopathological characteristics in patients undergoing potentially curative surgery and adjuvant 5-FU chemotherapy for colorectal cancer (n=222) and survival.

  No adjuvant chemotherapy (n=172)   Adjuvant chemotherapy (n=50)  
  HR (95% CI) P-value HR (95% CI) P-value
Univariate analysis        
 Age (<65/65–74/⩾75) years 2.33 (1.48–3.68) <0.001 0.73 (0.31–1.71) 0.464
 Sex (male/female) 1.37 (0.77–2.46) 0.287 1.55 (0.55–4.36) 0.411
 Site (colon/rectum) 1.23 (0.69–2.21) 0.477 1.19 (0.43–3.29) 0.735
 Dukes stage (A/B/C) 1.75 (1.06–2.89) 0.029 3.36 (0.44–25.85) 0.245
 C-reactive protein (⩽10, >10 mg l−1) 2.39 (1.32–4.34) 0.004 6.68 (2.05–21.72) 0.002
 Albumin (⩾35/<35 g l−1) 1.42 (0.59–3.40) 0.433    
 
Multivariate analysis        
 Age (<65/65–74/⩾75) years 1.87 (1.13–3.09) 0.015 1.21 (0.47–3.15) 0.693
 Sex (male/female) 1.08 (0.55–2.09) 0.828 0.92 (0.26–3.22) 0.894
 Site (colon/rectum) 1.57 (0.81–3.07) 0.185 1.15 (0.31–4.27) 0.834
 Dukes stage (A/B/C) 1.39 (0.82–2.36) 0.219 2.56 (0.31–21.21) 0.384
 C-reactive protein (⩽10, >10 mg l−1) 2.10 (1.04–4.25) 0.039 5.57 (1.32–23.51) 0.019
 Albumin (⩾35/<35 g l−1) 1.18 (0.48–2.88) 0.721