Table 1. Selection of SNPs across RB1.

SNP ID	Genomic location	Nucleotide changea	SNPs chosen initially for genotyping	SNP reported by NIEHS with MAF>0.05	Tag SNP	Tagging SNP(s)	r p 2
rs1573601	Upstream	c>a		✓		rs1981434, rs4151540, rs3092904 (g/+/a haplotype)	0.93
rs1981434	Intron 1	c>g		✓	✓	rs1981434	1.0
rs2854345	Intron 2	a>g	✓	✓	✓	rs2854345	1.0
rs4151437	Intron 2	g>a		✓		rs4151551	0.80
rs4151438	Intron 2	c>g		✓	FAILb	rs2854345	0.19
rs520342	Intron 3	c>t	✓	✓	✓	rs520342	1.0
rs4151450	Intron 3	g>c		✓		rs399413	0.85
rs198619	Intron 7	t>a		✓		rs399413	0.84
rs4151510	Intron 11	g>a		✓		rs4151620	1.0
rs4151520	Intron 11	g>a		✓		rs520342	0.96
rs399413	Intron 12	g>a	✓	✓	✓	rs399413	1.0
rs4151540	Intron 17	->aa		✓	✓	rs4151540	1.0
rs198610	Intron 17	g>t	✓		?c	?
rs4151551	Intron 17	g>t	✓	✓		rs4151551	1.0
rs2227311	Intron 17	t>c	✓	✓	✓	rs4151620	1.0
rs2854344	Intron 17	g>a	✓		?c	?
rs9535032	Intron 17	a>g	✓		?c	?
rs425834	Intron 17	a>g		✓	✓	rs425834	1.0
rs1951775	Intron 17	g>t		✓		rs399413	0.85
rs198570	Intron 17	g>t		✓		rs3092904	1.0
rs4151580	Intron 18	g>a		✓	Not polymd	rs4151580	1.0
rs4151584	Intron 18	t>c		✓	FAILb	rs2854345	0.28
rs198580	Intron 19	a>g	✓		?c	?
rs198590	Intron 21	g>a		✓		rs520342	1.0
rs4151611	Intron 24	g>a		✓	✓	rs4151611	1.0
rs4151618	Intron 24	t>c		✓		rs4151611	1.0
rs4151620	Intron 24	c>g	✓	✓	✓	rs4151620	1.0
rs3092904	Intron 24	t>a	✓	✓	✓	rs3520342	0.98
rs4151636	Downstream	c>g		✓	✓	rs4151636	1.0

^aThe most common allele is given first.

^bThe SNP was initially selected for genotyping but the assay could not be designed.

^cThe contribution of the SNP to the tagging of other identified SNP could not be estimated.

^dThe SNP was not polymorphic in the British population.