Table 3. RB1 haplotype analysis using the 15 SNPs genotyped in the study set.

	Frequency
Haplotypea	Controls	Cases	OR (95% CI) compared to most common	P-value	OR (95% CI) compared to all others	P-value
000000000000000	0.38	0.37	Ref	—	0.94 (0.86–1.03)	0.19
111110000100010	0.16	0.17	1.12 (0.98–1.27)	0.09	1.09 (0.97–1.22)	0.16
000000010000000	0.13	0.13	0.99 (0.86–1.13)	0.86	0.94 (0.83–1.07)	0.33
000000100000000	0.10	0.09	1.01 (0.86–1.18)	0.92	0.97 (0.83–1.12)	0.64
101110001100010	0.07	0.06	0.94 (0.78–1.12)	0.47	0.90 (0.75–1.06)	0.21
Rareb	0.07	0.08	1.16 (1.03–1.32)	0.02	1.15 (1.02–1.28)	0.02

^aSNPs used for haplotype analysis have same order as Table 2. For each SNP, 0 represents the commonest allele and 1 the rarest allele.

^bRare haplotypes (⩽4%) were pooled.