Table 1. Patients characteristics.

	FOLFIRI (n=146)		FOLFOXIRI (n=137)
Characteristics	n	%	n	%
Age
Median (range)	66 (39–84)		66 (25–82)
⩾65 years	82	56	75	55
Sex
Male	82	58	76	55
Female	61	42	61	45
Performance status (ECOG)
0	55	38	49	36
1	74	51	73	53
2	17	11	15	11
Localisation
Colon	110	75	100	73
Rectum	36	25	37	27
Sites of disease
Liver	102	70	99	72
Lung	46	32	42	31
Other	63	43	61	46
Number of metastatic sites
1	59	40	55	40
2	63	43	57	42
⩾3	24	16	25	18
Median (range)	2 (1–4)		2 (1–6)
Metastases
Synchronous	63	43	66	48
Metachronous	83	57	70	52
Kohne prognostic index
Low risk	54	37	44	32
Intermediate risk	57	39	56	41
High risk	35	24	37	27
Prior therapy
Adjuvant chemotherapy	48	33	49	36
Adjuvant		18		17
Chemoradiotherapy		12		12