Table 2. Incidence of common toxicities with the FOLFIRI and FOLFOXIRI regimens (maximum toxicity per patient).

	FOLFIRI (146)	FOLFOXIRI (130)		FOLFIRI (146)	FOLFOXIRI (130)
	Any			Grade 3/4
	%	%	P-value	%	%	P-value
Neutropenia	60	73	NSa	28	35	0.192
Febrile neutropenia	6	9	NS	4	7	0.186
Thrombocytopenia	20	31	NS	4	2	0.4
Anaemia	59	60	NS	1	4	0.072
Nause/vomiting	45	52	NS	4.8	4.6	0.944
Diarrhoea	51	69	NS	10.9	27.7	0.0001
Mucocitis	18	21	NS	4	5	0.748
Neurological	11	59	0.001	0	5.8	0.001
Cutaneous	15	21	NS	3	4	0.133
Alopecia	56	74	NS	12	32	0.0001
Fatigue	36	41	NS	5	5.6	0.944

^aNS, nonsignificant.