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. 2006 Feb 28;94(6):771–775. doi: 10.1038/sj.bjc.6603019

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Copyright © 2006 Cancer Research UK

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EGFR signalling leads to the formation of wing veins by overriding Groucho-mediated repression. (A) Shown are abbreviated presentations of the EGFR and Notch signalling pathways. (B) A photograph of a Drosophila wing, with the veins numbered (L1–L5). Below, a schematic illustration of adjacent vein and intervein regions, depicting how MAPK phosphorylation of Gro may relieve transcriptional silencing by multiple antivein Gro-dependent repressors, promoting the formation of wing veins.