Table 1. Risk of non-Hodgkin's lymphoma associated with hormone replacement therapy among women aged 40 years or older in North Jutland County, Denmark.
| Number of NHL cases | Person-years | Age-standardised incidence rate (/105 person-years) | Standardised rate ratio (95% CI) | Adjusted relative riska (95% CI) | |
|---|---|---|---|---|---|
| Unexposed | 310 | 1 247 302 | 24.2 | Reference | Reference |
| HRT-exposed (1+ prescriptions) | 40 | 179 838 | 25.7 | 1.06 (0.76–1.44) | 0.99 (0.71–1.39) |
| Recency | |||||
| <2 years since latest prescription | 25 | 119 914 | 22.9 | 0.95 (0.61–1.40) | 0.98 (0.65–1.49) |
| 2–5 years since latest prescription | 6 | 33 127 | 22.5 | 0.93 (0.34–2.03) | 0.78 (0.35–1.76) |
| >5 years since latest prescription | 9 | 26 796 | 30.5 | 1.26 (0.58–2.39) | 1.24 (0.63–2.42) |
| Number of HRT prescriptions | |||||
| 1 | 6 | 29 292 | 24.0 | 0.99 (0.36–2.16) | 0.91 (0.41–2.05) |
| 2–4 | 5 | 37 507 | 16.0 | 0.66 (0.22–1.55) | 0.63 (0.26–1.52) |
| 5–9 | 8 | 32 437 | 34.7 | 1.43 (0.62–2.83) | 1.16 (0.57–2.35) |
| 10–19 | 10 | 35 463 | 33.2 | 1.37 (0.66–2.52) | 1.31 (0.69–2.48) |
| 20+ | 11 | 45 139 | 22.9 | 0.95 (0.47–1.69) | 0.98 (0.53–1.80) |
a
Adjusted for age and calendar period.