Table 4A. Comparison of survival in patient groups with different expression profiles of E-cadherin and Snail in primary ovarian cancer using multivariate Cox proportional hazard regression adjusted for patient age.

			95% CI for HR
Primary ovarian cancer (n=48)	P	HR	Lower	Upper
E-cadherin+/Snail− (n=23)a		1.00
E-cadherin+/Snail+ (n=13)	0.590	1.28	0.521	3.150
E-cadherin−/Snail− (n=7)	0.165	2.13	0.733	6.191
E-cadherin−/Snail+ (n=5)	0.002#	5.91	1.973	18.036
Age (years)	0.890	1.01	0.973	1.032

CI=confidence interval; HR=hazard ratio for the occurrence of death; +=preserved immunoreactivity for E-cadherin (3+) or Snail positive (1+, 2+, and 3+); −=reduced immunoreactivity for E-cadherin (0, 1+, and 2+) or Snail negative (0).

^aWas set as the reference group.

^#Significant according to the adjusted significance level.

n, number of patients.

Bold value signifies P-value <0.05.