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. 2008 Jan 8;98(2):388–398. doi: 10.1038/sj.bjc.6604168

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Copyright © 2008 Cancer Research UK

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Representative tumour sections 90 min after treatment with bleomycin, application of electric pulses or electrochemotherapy. Brown regions are the cells stained with pimonidazole, a marker of tumour hypoxia. Note marked differences in the extent of hypoxic regions between groups without application of electric pulses (control and bleomycin) and those with the application of electric pulses (electric pulses and electrochemotherapy).