Table 2. Relation between Rad51 expression and clinicopathological parameters in 235 cases of NSCL.
|
Rad51 (cases and percentage)
|
|||
|---|---|---|---|
| Parameters | −a | +b | P-value |
| Total | 240 (70.6%) | 100 (29.4%) | |
| Age | |||
| ⩽59 years | 119 (73.5%) | 43 (26.5%) | 0.269 |
| >59 years | 121 (68.0%) | 57 (32.0%) | |
| Sex | |||
| Male | 171 (70.1%) | 73 (29.9%) | 0.744 |
| Female | 69 (71.9%) | 27 (28.1%) | |
| T status | |||
| 1 | 14 (66.7%) | 7 (33.3%) | 0.771 |
| 2 | 124 (72.9%) | 46 (27.1%) | |
| 3 | 77 (67.5%) | 37 (32.5%) | |
| 4 | 25 (71.4%) | 10 (28.6%) | |
| N status | |||
| 0 | 105 (70.5%) | 44 (29.5%) | 0.513 |
| 1 | 54 (77.1%) | 16 (22.9%) | |
| 2 | 76 (67.3%) | 37 (37.2%) | |
| 3 | 5 (62.5%) | 3 (37.5%) | |
| M status | |||
| 0 | 226 (70.8%) | 93 (29.2%) | 0.684 |
| 1 | 14 (66.7%) | 7 (33.3%) | |
| Stage | |||
| I | 71 (74.7%) | 24 (25.3%) | 0.756 |
| II | 56 (70.0%) | 24 (30.0%) | |
| III | 99 (68.8%) | 45 (31.3%) | |
| IV | 14 (66.7%) | 7 (33.3%) | |
| Histology | |||
| SCCc | 85 (72.6%) | 32 (27.4%) | 0.891 |
| ADCd | 116 (68.6%) | 53 (31.4%) | |
| ADSCCe | 29 (72.5%) | 11 (27.5%) | |
| Othersf | 10 (71.4%) | 4 (28.6%) | |
| Tumour grade | |||
| G1 | 41 (66.1%) | 21 (33.9%) | 0.535 |
| G2 | 109 (66.7%) | 52 (33.3%) | |
| G3 | 90 (76.9%) | 27 (23.1%) | |
−=low-level expression of Rad51.
+=high-level expression of Rad51.
SCC=squamous cell carcinoma.
ADC=adenocarcinoma.
ADSCC=adenosquamous carcinoma.
others include anaplastic large-cell carcinoma, sarcoma, adenoid cystic carcinoma, mucoepidermoid carcinoma and carcinoid tumour.