Table 3. Expression of the studied factors according to clinical parameters.
EGFR expression
|
P53 expression
|
VEGF expression
|
||||||||
---|---|---|---|---|---|---|---|---|---|---|
Clinical parameters and outcome variables | Neg | M pos | D pos | P | Neg | Pos | P | Neg | Pos | P |
Age | ||||||||||
< 55 yo | 10 | 18 | 04 | 0.299 | 09 | 23 | 0.731 | 15 | 17 | 0.091 |
55–65 yo | 10 | 25 | 07 | 15 | 27 | 27 | 15 | |||
> 65 yo | 14 | 12 | 07 | 12 | 21 | 24 | 09 | |||
Gender | ||||||||||
Male | 33 | 46 | 15 | 0.087 | 31 | 63 | 0.937 | 59 | 35 | 0.752 |
Female | 01 | 09 | 03 | 05 | 08 | 07 | 06 | |||
Diff | ||||||||||
WD | 12 | 21 | 11 | 0.124 | 18 | 26 | 0.126 | 34 | 10 | 0.012 |
MPD | 22 | 34 | 07 | 18 | 45 | 32 | 31 | |||
pT | ||||||||||
pT1 | 14 | 16 | 04 | 0.312 | 09 | 25 | 0.284 | 23 | 11 | 0.386 |
pT2-T3 | 20 | 39 | 14 | 27 | 46 | 43 | 30 | |||
pN | ||||||||||
N0 | 24 | 33 | 09 | 0.196 | 19 | 47 | 0.177 | 42 | 24 | 0.598 |
N+ | 10 | 22 | 09 | 17 | 24 | 24 | 17 | |||
Vasc. Inv. | ||||||||||
No | 28 | 32 | 12 | 0.061 | 23 | 49 | 0.593 | 48 | 24 | 0.128 |
Yes | 06 | 23 | 06 | 13 | 22 | 18 | 17 | |||
Local recurrence | ||||||||||
No | 25 | 35 | 11 | 0.552 | 20 | 51 | 0.092 | 44 | 27 | 0.931 |
Yes | 09 | 20 | 07 | 16 | 20 | 22 | 14 | |||
Metastasis occurrence | ||||||||||
No | 21 | 28 | 07 | 0.278 | 21 | 35 | 0.376 | 34 | 22 | 0.829 |
Yes | 13 | 27 | 11 | 15 | 36 | 32 | 19 | |||
EGFR status | ||||||||||
Negative | 12 | 22 | 0.800 | 21 | 13 | 0.268 | ||||
M pos | 17 | 38 | 31 | 24 | ||||||
D pos | 07 | 11 | 14 | 04 | ||||||
P53 positivity | ||||||||||
Negative | 19 | 17 | 0.177 | |||||||
Positive | 47 | 24 | ||||||||
Total | 34 31.8% | 55 51.4%° | 18 16.8% | 36 33.6% | 71 66.4% | 66 61.7 | 41 38.3 |
yo=years old, Diff=differenciation, WD=well differentiated, MPD=moderately to poorly differentiated, Vasc. Inv.=vascular invasion, M pos=mosaic positivity, D pos=diffuse positivity, neg=negative, pos=positive.