Table 4. Logistic regression analysis of response to Iressa.
| Coefficient (s.e.) | Odds ratio | 95% confidence interval | P-value | |
|---|---|---|---|---|
| Gender | 0.42 | |||
| Female (n=58) | 0.42 (0.52) | 1.53 | 0.55, 4.24 | |
| Male (n=52) | — | 1 | — | |
| Smoker | 0.005 | |||
| No (n=66) | 1.80 (0.64) | 6.08 | 1.72, 21.43 | |
| Yes (n=44) | — | 1 | — | |
| Age in years | 0.25 | |||
| <60 (n=65) | −0.57 (0.49) | 0.57 | 0.22, 1.49 | |
| ⩾60 (n=45) | — | 1 | — | |
| No. of lines of chemotherapy | 0.62 | |||
| 0–1 (n=32) | −0.26 (0.52) | 0.77 | 0.28, 2.15 | |
| ⩾2 (n=78) | — | 1 | — | |
| ECOG status | 0.53 | |||
| 0–1 (n=79) | 0.34 (0.54) | 1.40 | 0.48, 4.07 | |
| 2–4 (n=31) | — | 1 | — | |
| Squamous cell histology | 0.99 | |||
| Yes (n=11) | −19.55 (11737.8) | <0.001 | 0, ∞ | |
| No (n=99) | — | 1 | — | |
| Constant | −2.01 (0.75) | 0.13 | — | 0.007 |
s.e.=standard error of regression coefficient.