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| Toxicity profile | Grade 1 (%) | Grade 2 (%) | Grade 3 (%) | Grade 4 (%) |
|---|---|---|---|---|
| Rash | 29 (26) | 5 (5) | 3 (3) | 1 (1) |
| Eyes | 8 (7) | 0 | 0 | 0 |
| Diarrhoea | 10 (9) | 0 | 0 | 0 |
| Asthenia | 1 (1) | 2 (2) | 0 | 1 (1) |
| Leucopenia | 1 (1) | 1 (1) | 0 | 0 |
| Thrombocytopenia | 0 | 0 | 1 (1) | 0 |
| Anaemia | 17 (16) | 5 (5) | 1 (1) | 0 |
| Bilirubinemia | 4 (4) | 1 (1) | 0 | 0 |
| Transaminitis | 13 (12) | 3 (3) | 1 (1) | 5 (5) |
