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. 2005 Oct 25;93(10):1117–1121. doi: 10.1038/sj.bjc.6602849

Table 3. Acute toxic effects (N=37).

  Grade (% of patients)
 
  1 2 3 4 Grade 3/4 (%)
Haematologic
 Anaemia 13 (35.1) 6 (16.2) 2 (5.4) 1 (2.7) 8.1
 Leukopenia 6 (16.2) 8 (21.6) 2 (5.4) 1 (2.7) 8.1
 Neutropenia 7 (18.9) 6 (16.2) 1 (2.7) 1 (2.7) 5.4
 Thrombocytopenia 12 (32.4) 2 (5.4) 1 (2.7)   2.7
 Febrile neutropenia     1 (2.7)   2.7
 
Nonhaematologic
 Nausea 11 (29.7) 12 (32.4) 5 (13.5) 1 (2.7) 16.2
 Vomiting 9 (24.3) 10 (27.0) 3 (8.1)   8.1
 Mucositis 2 (5.4) 10 (27.0) 17 (45.9) 8 (21.6) 67.6
 Dermatitis (in-field) 3 (8.1) 12 (32.4) 7 (18.9) 2 (5.4) 24.3
 Diarrhoea 4 (10.8) 3 (8.1) 1 (2.7)    
 Hand–foot syndrome 12 (32.4) 4 (10.8)