Table 1. Doses of gemcitabine, cisplatin and tipifarnib and number of patients included per dose level.

Dose level	Gemcitabine (mg m−2) days 1 and 8	Cisplatin (mg m−2) day 1	Tipifarnib (mg twice daily) days 1–7	n
1	750	75	100	4
2	750	75	200	11
3	1000	75	200	6
4	1000	100	200	7
5	1000	100	300	3