Table 1. Characteristics at baseline of patients with asymptomatic colorectal cancer in two trials.
|
Australasia
|
Canada
|
|||
|---|---|---|---|---|
| Immediate | Delayed | Immediate | Delayed | |
| Characteristic | n=50 | n=51 | n=34 | n=33 |
| Median age (years) | 66.8 | 65.3 | 67.4 | 63.7 |
| Age range (years) | 46–80 | 36–77 | 56–80 | 50–78 |
| Aged >70 years (n, %) | 17 (34) | 8 (16) | 13 (38) | 7 (21) |
| Female (n, %) | 12 (24) | 14 (27) | 8 (24) | 9 (27) |
| ECOG performance status | ||||
| 0 (n, %) | 42 (84) | 38 (75) | 34 (100) | 33 (100) |
| 1 (n, %) | 8 (16) | 13 (25) | 0 | 0 |
| Karnofsky performance status | ||||
| 100 (n, %) | NA | NA | 14 (41) | 21 (64) |
| 90 (n, %) | NA | NA | 20 (59) | 12 (36) |
| Measurable disease | 50 (100) | 51 (100) | 24 (71) | 25 (76) |
| Sites of disease a | ||||
| Peritoneal cavity (n, %) | NA | NA | 5 (15) | 4 (12) |
| Liver (n, %) | 39 (83) | 34 (71) | 23 (68) | 24 (73) |
| Lung (n, %) | 10 (21) | 17 (35) | 12 (35) | 10 (30) |
| Lymph nodes (n, %) | 7 (15) | 9 (19) | NA | NA |
| Other (n, %) | 9 (19) | 11 (23) | 21 (62) | 12 (36) |
| Weight loss (n, %) | 7 (14) | 9 (18) | NA | NA |
| Prior adjuvant chemotherapy (n, %) | 14 (28) | 12 (24) | 9 (26) | 8 (24) |
| Stage IV at first presentation (n, %) | 19 (38) | 12 (24) | NA | NA |
| Disease-free interval >12 months (n, %) | NA | NA | 14 (41) | 13 (39) |
| Treatment-free interval (months) | NA | NA | 9–58 | 13–46 |
NA=not available.
a
Patients could have more than one site of disease.