Table 3. Two hypothetical treatments (A and B).

Percentage of patients with a complete/partial tumour response	Median survival, months (95% CI)	Percentage of patients with progressive disease	Median survival, months (95% CI)	Median time to progression (months)	Median survival, months (95% CI)
On treatment A		On treatment A		On treatment A
30	20	12	20	10	20
On treatment B		On treatment B		On treatment B
40	22 (20–24)	10	21 (20–22)	12	23 (21–24)
50	25 (22–28)	8	22 (20–23)	16	26 (23–29)
60	28 (24–33)	6	23 (21–25)	20	29 (25–34)

The estimated effect on survival using treatment B compared to A based on arbitrary estimates of tumour response and disease progression, and the regression analyses in Figure 1.

CI, confidence interval (based on the 95% CI of the predicted mean value in the regression analysis).