Table 1. mtDNA changes detected in the entire sequence of Control 1, 2 and UC-Case 1–3.

Control 1			Control 2			UC-Case 1			UC-Case 2			UC-Case 3
Position	Gene	Change	Position	Gene	Change	Position	Gene	Change	Position	Gene	Change	Position	Gene	Change
248	D-loop	del A	741	12SrRNA	A → G	191	D-loop	del A	500	D-loop	del C	1074	12SrRNA	ins C
2472	16SrRNA	del A	2687	16SrRNA	del C	200	D-loop	A → C	514	D-loop	del CA	1080	12SrRNA	ins C
3969	ND1	C → T	6479	COI	ins A	490	D-loop	A → C	751	12SrRNA	A → G	2036	12SrRNA	ins C
4769	ND2	A → G	8639	ATPase6	T → C	1000	12SrRNA	T → A	2686	16SrRNA	G → C	3106	12SrRNA	del C
6392	COI	T → C	8850	ATPase6	A → G	1438	12SrRNA	A → G	4386	Q	T → C	4032	ND1	del CC
9053	ATPase6	G → A	8860	ATPase6	A → G	1486	12SrRNA	C → G	4769	ND2	A → G	4919	ND2	ins T
10 309	ND3	T → A	11 720	ND4	G → A	3010	12SrRNA	G → A	4958	ND2	A → G	5101	ND2	C → T
10 590	ND4L	T → G	15 326	Cyt.b	A → G	3285	L	T → G	5895	COI	ins C	6179	COI	G → A
11 947	ND4	A → C				3338	ND1	T → G	6455	COI	C → T	6456	COI	G → A
11 955	ND4	A → C				4662	ND2	A → G	7337	COI	G → A	7904	COII	ins G
						4768	ND2	T → G	7852	COII	G → A	7917	COII	ins G
						4883	ND2	C → T	8861	ATPase6	C → G	8021	COII	ins A
						5178	ND2	C → T	10 999	ND4	C → G	8483	ATPase8	A → T
						5942	COI	A → G	11 084	ND4	A → G	8494	ATPase8	A → T
						9860	COIII	T → G	11 102	ND4	ins G	8684	ATPase6	C → T
						9883	COIII	T → G	11 771	ND4	C → G	8860	ATPase6	A → G
						11 853	ND4	C → T	11 853	ND4	C → T	9540	COIII	T → C
						11 247	ND4	C → G	12 417	ND5	C → T	9572	COIII	C → T
						11 457	ND4	C → G	12 705	ND5	C → T	10 027	ND3	ins G
						11 712	ND4	C → G	13 586	ND5	C → T	10 873	ND4	T → C
						11 719	ND4	G → A	13 768	ND5	T → C	11 335	ND4	T → C
						11 956	ND4	C → T	14 364	ND6	G → A	12 705	ND5	C → T
						14 570	ND6	C → G	14 783	Cyt.b	T → C	14 783	Cyt.b	T → C
						16 147	D-loop	C → T	15 043	Cyt.b	G → A	15 043	Cyt.b	G → A
						16 245	D-loop	C → T	16 209	D-loop	T → C	16 184	D-loop	C → T
												16 298	D-loop	T → C
												16 319	D-loop	G → A
												16 524	D-loop	ins G

ND=NADH (reduced nicotinamide adenine dinucleotide) dehydrogenase; CO=cytochrome c oxidase; ATPase, ATP synthase; Cyt b, cytochrome b.

F, V, L, I, Q, M, W, A, N, C, Y, S, D, K, G, R, H, E, T, and P=tRNAs for phenylalanine, valine, leucine, isoleucine, glutamine, methionine, tryptophan, alanine, asparagine, cysteine, tyrosine, serine, aspartate, lysine, glycine, arginine, histidine, glutamate, threonine, and proline, respectively.

ins=insertion; del=deletion.