Table 1. Analysis of the neoplastic phenotype of the UbcH10-transfected rat thyroid cell lines.
| Cell line | Doubling time (h) | Colony-forminga efficiency (%) | Tumourb incidence |
|---|---|---|---|
| PC CL 3 | 24 | 0 | 0/4 |
| PC UbcH10 CL1 | 24 | 0 | 0/4 |
| PC UbcH10 CL2 | 23 | 0 | 0/4 |
| PC MPSV | 18 | 70 | 4/4 |
Colony-forming efficiency was calculated by the formula (number of colonies formed/number of plated cells) × 100.
Tumorigenicity was assayed by injecting 2 × 106 cells into athymic mice (4–6 weeks old).