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. 2005 Aug 2;93(4):441–449. doi: 10.1038/sj.bjc.6602713

Table 1. Evaluation of selected serum chemistries 5 days after intratumoral injection of AdCA-mIFN.

  AdCA-mIFN
AdCA-AP
No treatment
Dose (PFU): × 108 2.5 1.0 0.25 2.5 —
Mouse IFN concentration
 Tumour (pg g−1): × 103 252.3±292.2 53.0±30.0 14.3±13.4 1.4±0.6 0.8±0.2
 Serum (pg ml−1): × 103 1.7±0.9 0.3±0.1 0.3±0.2 0.2±0.1 0.2±0.1
           
 Albumin (g dl−1) 2.8±0.3 2.9±0.4 2.8±0.4 2.7±0.1 2.9±0.3
 Alk. phos. (IU l−1) 231±71 186±29 199±44 186±21 218±81
 Amylase (U l−1) 13 910±3932 16 595±6937 17 790±453 14 850±353 10 269±3922
 BUN (mg dl−1) 19.1±1.6 23.6±6.4 21.2±2.4 22.7±1.3 23.9±4.0
 Creatinine (mg dl−1) 0.08± 0.02 0.09± 0.02 0.1±0.01 0.09±0.02 0.11±0.03
 LDH (IU l−1) 379± 69 316±68 560±244 486±252 368±216
 AST (IU l−1) 126±4 101±42 93±34 68±17 70±23
 ALT (IU l−1) 54±32 28±4 25±7 18±10 19±5
 T. bil. (mg dl−1) 0.05±0.01 0.04±0.01 0.05±0.01 0.06±0.01 0.04±0.01