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| Clinical trial design (48 trials) | Type of end point (primary) (48 trials) | Difference in survival, when available (13 trials) |
|---|---|---|
| RCT 25 | Survival 4 | Range 0–3.7 months |
| SAT 19 | Resp. rate 30 | Mean 1.5 (months) |
| NC-RCT 4 | TTP/PFS 14 | Median 1.2 (months) |
RCT=randomised clinical trial; SAT=single-arm trial; NC-RCT=noncomparative RCT; TTP=time to progression; PFS=progression-free survival.
