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. 2005 Aug 16;93(5):557–564. doi: 10.1038/sj.bjc.6602742

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Copyright © 2005 Cancer Research UK

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Kaplan–Meyer analysis for expression of IFNAR2. Immunohistochemical analysis was performed in 13 biopsy samples. The expression rate of IFNAR2 was 69.2% (nine out of 13). (A) The median progression-free survival rate was 12.6 months for IFNAR2-positive cases and 1.7 months for IFNAR2-negative cases. The 1-, 2-, and 3-year progression-free survival rates were 30.5, 0, and 0%, respectively, for IFNAR2-positive cases, 0, 0, and 0%, respectively, for IFNAR2-negative cases. There was a significant correlation between positive and negative cases (P=0.0002). (B) The median overall survival rate was 24.4 months for IFNAR2-positive cases and 3.4 months for IFNAR2-negative cases. The overall survival rates at 1, 2, and 3 years of IFNAR2-positive patients (n=9) (88.9, 55.6 and 22.2%, respectively) were significantly higher than the rates (0, 0, and 0%, respectively) of IFNAR2-negative patients (n=4). There was a significant difference between positive and negative cases (P<0.0001).