Table 3. Relative risk of premenopausal breast cancer in relation to (A) perceived body fatness at age 10 years and (B) participation in sports at young ages, with and without adjustment for body fatness, participation in sports at different ages and menstrual characteristics.
Thin
|
Average
|
Plump
|
||||
---|---|---|---|---|---|---|
(A) Model/perceived body fatness at age 10 years | RRa | 95% FCIb | RRa | 95% FCIb | RRa | 95% FCIb |
Multivariate-adjustedc | 1.05 | 0.94–1.17 | 1.00 | 0.89–1.12 | 0.85 | 0.72–0.99 |
Multivariatec+participation in sports at all young ages | 1.05 | 0.93–1.17 | 1.00 | 0.89–1.12 | 0.84 | 0.72–0.99 |
Multivariatec+participation in sports at diagnosis/pseudodiagnosis | 1.04 | 0.93–1.17 | 1.00 | 0.89–1.12 | 0.84 | 0.72–0.99 |
Multivariatec+menstrual characteristicsd | 1.06 | 0.95–1.20 | 1.00 | 0.89–1.12 | 0.84 | 0.72–0.99 |
0–1 h week−1
|
2–3 h week−1
|
4+ h week−1
|
||||
---|---|---|---|---|---|---|
(B) Model/average duration of sports participation at ages 12–30 years | RRe | 95% FCIb | RRe | 95% FCIb | RRe | 95% FCIb |
Multivariate-adjustedc | 1.00 | 0.90–1.13 | 0.99 | 0.89–1.11 | 1.01 | 0.88–1.16 |
Multivariatec+body fatness at age 10 | 1.00 | 0.88–1.13 | 0.99 | 0.88–1.11 | 1.00 | 0.87–1.16 |
Multivariatec+body mass index (BMI) at age 20 years | 1.00 | 0.88–1.13 | 0.98 | 0.87–1.10 | 1.00 | 0.86–1.14 |
Multivariatec+BMI at diagnosis/pseudodiagnosis | 1.00 | 0.88–1.13 | 0.99 | 0.88–1.11 | 1.01 | 0.87–1.16 |
Multivariatec+menstrual characteristicsd | 1.00 | 0.88–1.13 | 0.98 | 0.88–1.10 | 1.00 | 0.87–1.15 |
Relative risk, compared with women who reported to be of average body fatness at age 10 years.
Floated confidence intervals (see Material and Methods).
Stratified by age and recruitment region, adjusted for parity, age at first birth, height, use of oral contraceptives and alcohol consumption.
Additional adjustments for age at menarche, time from menarche to onset of regular cycles and irregular menstrual cycles at ages 20–30 years.
Relative risk, compared with women who reported to participate 1 h or less per week in sports at young ages.