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. 2005 Oct 25;93(9):1011–1018. doi: 10.1038/sj.bjc.6602823

Table 2. Plasma pharmacokinetics of NU7026 and its metabolites NU7199 and NU7200 following administration of NU7026 at 5 mg kg−1 i.v. to mice.

Compound Cmax (nmol l−1) Tmax (h) AUC last (nmol l h−1) t1/2 (h) Cl obs. (l h−1) Vd (l)
7026 5123 0 3616 1.22 0.09 0.16
7199 705 0.25 414 0.2 0.82 0.23
7200 293 0.25 143 0.16 2.44 0.55

Parameters are Cmax (maximum concentration), AUC (area under the concentration vs time curve), Cl (Clearance), t1/2 (half-life), Vd (volume ofz distribution based on the elimination phase).