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. 2005 Oct 25;93(9):1011–1018. doi: 10.1038/sj.bjc.6602823

Table 3. Plasma pharmacokinetics of NU7026 and NU7107 following administration at 20 mg kg−1 i.p. to mice.

Compound Cmax (nmol l−1) Tmax (h) AUC last (nmol l h−1) t1/2 (h) Cl obs. (l h−1) Vd (l)
7026 5123 0.083 7349 0.87 0.44 0.55
7107 10390 0.25 12165 0.79 0.11 0.12

Parameters are Cmax (maximum concentration), AUC (area under the concentration vs time curve), Cl (clearance), t1/2 (half-life), Vd (volume of distribution based on the elimination phase).