Table 1. Relation of FANCF methylation status and clinicopathologic variables in 54 cases of advanced ovarian cancer.
| FANCF methylated, n=7 (column %) | FANCF unmethylated, N=46 (column %) | Pearson's χ2/Fisher's exact P | |
|---|---|---|---|
| Median age (range, years) | 64.1 (42.3–65.9) | 59.3 (22.8–76.4) | 0.937* |
| Age <65 | 3 (42.9%) | 36 (53.7%) | 0.701 |
| Age >65 | 4 (57.1%) | 31 (46.3%) | |
| Performance status | |||
| 0 | 2 (28.6%) | 22 (47.8%) | 0.688 |
| 1 | 3 (42.9%) | 15 (32.6%) | |
| 2 | 2 (28.6%) | 8 (17.4%) | |
| 3 | 0 (0%) | 1 (2.2%) | |
| Stage | |||
| IIB/IIC/III | 5 (71.4%) | 36 (78.3% | 0.462 |
| IV | 2 (28.6%) | 9 (19.6%) | |
| Missing | 0 (0%) | 1 (2.1%) | |
| Histology | |||
| Serous | 6 (85.27%) | 27(58.7%) | 0.136 |
| Nonserous | 0 (0%) | 12 (26.1%) | |
| Missing | 1 (14.3%) | 7 (15.2%) | |
| Tumour grade | |||
| Well-moderate | 3 (42.9%) | 21 (45.7%) | 0.449 |
| Poorly differentiated | 4 (57.1%) | 18 (39.1%) | |
| Missing | 0 (0%) | 87 (15.2%) | |
| Residual tumour volume | |||
| <1 cm | 1 (14.3%) | 13 (28.3%) | 0.383 |
| ⩾1 cm | 6 (85.7%) | 32 (69.6%) | |
| Missing | 0 (0%) | 1 (2.1%) | |
*Mann–Whitney U-test (two-sided) P-value.