Table 2. Number of breast and ovarian cancer cases among the relatives of index cases, by the age at diagnosis and the mutation status of the index case.
BRCA1 carriers
|
BRCA2 carriers
|
Noncarriers
|
||||
---|---|---|---|---|---|---|
Age group (years) | BC | OC | BC | OC | BC | OC |
<20 | 0 | 0 | 0 | 0 | 0 | 0 |
20–29 | 6 | 7 | 5 | 0 | 7 | 4 |
30–39 | 58 | 25 | 34 | 0 | 79 | 2 |
40–49 | 84 | 10 | 55 | 2 | 180 | 10 |
50–59 | 36 | 9 | 46 | 13 | 135 | 12 |
60–69 | 19 | 9 | 28 | 3 | 96 | 5 |
70+ | 12 | 3 | 20 | 4 | 78 | 12 |
BC=breast cancer; OC=ovarian cancer.