Table 5. Association of mutation of p53, tumour stage and the frequency of LOH of the p53 gene in oral cavity cancer.

Mutation of p53	Tumour stage	LOH/informative cases (%)	OR (95% CI)*	Lost Pro allele/LOH cases (%)	OR (95% CI)
No	I–III	7/21 (33.3)	1	4/7 (57.1)	1
Yes	I–III	12/28 (42.9)	1.50 (0.40–5.75)	7/12 (58.3)
No	IV	14/27 (51.0)	2.15 (0.57–8.35)	11/14 (78.6)	2.42 (0.56–10.77)
Yes	IV	12/18 (66.7)	4.00 (0.88–19.32)	9/12 (75.0)
Total		45/94 (47.9)		31/45 (68.9)

^*P=0.03 by χ² trend test.