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Spectra of somatic EGFR mutations. Location of somatic mutations found in 60 NSCLC, 48 sporadic and 24 hereditary (BRCA1/2 mutation positive) breast cancers. Exons are shown as bars with intronic regions as lines. For breast cancer samples, labels above each bar/line indicate mutations in the stroma, and labels below denote mutations found in neoplastic epithelium. Green labels indicate silent variants.
