Table 1. Selected characteristics of the study population.
Cases (n=613) | % | Controls (n=1082) | % | P-valuea | |
---|---|---|---|---|---|
Mean age (s.d.) | 42.4 (5.8) | 42.6 (5.7) | |||
Menopausal status | |||||
Premenopausal | 483 | 78.8 | 874 | 80.8 | |
Postmenopausal | 34 | 5.6 | 67 | 6.2 | |
Unknown | 96 | 15.7 | 141 | 13.0 | 0.30 |
First-degree family history | |||||
No | 536 | 87.4 | 1024 | 94.6 | |
Yes | 77 | 12.6 | 58 | 5.4 | <0.01 |
Parity | |||||
0 | 136 | 22.2 | 228 | 21.1 | |
1–2 children | 414 | 67.5 | 680 | 62.9 | |
3+ children | 63 | 10.3 | 174 | 16.1 | <0.01 |
Breastfeeding b | |||||
0 | 153 | 32.1 | 247 | 28.9 | |
1–12 months | 289 | 60.6 | 501 | 58.7 | |
12+ months | 35 | 7.3 | 106 | 12.4 | 0.01 |
Education | |||||
Low | 80 | 13.1 | 149 | 13.8 | |
Intermediate | 412 | 67.2 | 679 | 62.8 | |
High | 121 | 19.7 | 254 | 23.5 | 0.15 |
Smoking | |||||
Never active | 271 | 44.2 | 515 | 47.6 | |
Former smoker | 132 | 21.5 | 258 | 23.8 | |
Current smoker | 210 | 34.3 | 309 | 28.6 | 0.05 |
Alcohol consumption (g day on average−1) | |||||
0 | 117 | 19.1 | 176 | 16.3 | |
1–5 | 233 | 38.0 | 454 | 42.0 | |
6–11 | 113 | 18.4 | 239 | 22.1 | |
12+ | 150 | 24.5 | 213 | 19.7 | 0.02 |
ADH1B genotypes | |||||
*1/*1 | 548 | 89.4 | 973 | 89.9 | |
*1/*2 | 62 | 10.1 | 107 | 9.9 | |
*2/*2 | 3 | 0.5 | 2 | 0.2 | 0.53c |
s.d.=standard deviation; ADH1B=alcohol dehydrogenase 1B.
χ2 test used.
Among parous women only.
Fisher's exact test used.