Table 2. Clinical parameters and the concentration of the 80 kDa serum fragment are tested in an univariate and a multivariate regression model for association with outcome.
| Variable | P-value | Hazard ratio | 95% CI |
|---|---|---|---|
| Univariate Cox's proportional-hazard model | |||
| Race | 0.49 | 1.16 | (0.76–1.79) |
| Age (years) | 0.23 | 1.03 | (0.78–2.14) |
| Preoperative PSA (ng ml−1) | 0.83 | 1.004 | (0.97–1.05) |
| Gland weight (g) | 0.17 | 0.98 | (0.95–1.0) |
| Gleason sum | <0.001 | 2.49 | (1.62–3.84) |
| Multifocality | 0.67 | 1.27 | (0.43–3.78) |
| Extraprostatic extension | <0.001 | 10.94 | (4.22–28.37) |
| Seminal vesicle involvement | 0.002 | 4.34 | (1.74–10.81) |
| Surgical margin | 0.001 | 4.66 | (1.91–11.36) |
| Tumour stage | <0.001 | 2.67 | (1.69–4.22) |
| 80 kDa e-cadherin fragment | 0.79 | 1.12 | (0.45–2.65) |
| Multivariate (backward stepwise; Wald) | |||
| Gleason sum | 0.007 | 2.16 | (1.24–4.25) |
| Extraprostatic extension | 0.007 | 5.34 | (1.60–17.84) |
95% CI=95% confidence interval; PSA=prostate-specific antigen.