Table 1. Summary of clinicopathological and microsatellite features of colorectal cancer samples used for construction of the classifier (training set).
|
Localisation in colon
|
Tumour stage
N (Danish, Finnish) |
|||||
|---|---|---|---|---|---|---|
| Patient group | N (Danish, Finnish) | Median age (range) | Right (Danish, Finnish) | Left (Danish, Finnish) | II | III |
| All samples | 118 (44,75) | 62.0 (32–87) | 44 (7,37) | 74 (36,38) | 36 (14,22) | 65 (23,42) |
| Normala | 17 (6,11) | 57.7 (34–80) | 10 (3,7) | 7 (3,4) | NA | NA |
| Sporadic microsatellite unstable tumoursb | 19 (4,15) | 66.8 (44–87) | 11 (3,8) | 8 (1,7) | 8 (2,6) | 11 (2,9) |
| Hereditary microsatellite unstable tumoursb,c,d | 15 (3,12) | 49.6 (32–75) | 6 (1,5) | 9 (2,7) | 10 (2,8) | 5 (1,4) |
| Microsatellite stable tumoursb | 67 (30,37) | 61.0 (36–85) | 12 (0,12) | 55 (30,25) | 18 (10,8) | 49 (20,29) |
NA=not applicable.
Normal biopsy taken from the resection edge of a tumour.
According to microsatellite analysis.
According to Amsterdam Criteria 1.
With known germline mutations.