Table 2. Treatment effects upon MTCRII.

Treatment	Mice (n)	Total crypt no.	Total MT-immunopositive crypt number	Patches ⩾2 MT-immunopositive crypts	Frequency of MT-immunopositive foci
1. Water only	5	36 433±2053	1.134±0.34	0.10±0.06	1.130±0.33
2. DMSO only	5	33 292±2888	0.974±0.29	0	0.97±0.29
3. Continuous 1% λCgN	5	37 025±2091	0.88±0.32	0	0.88±0.33
4. Continuous 4% λCgN	5	38 657±1149	1.31±0.32	0	1.31±0.32
5. MNU only (62.5 mg kg−1)	10	29 750±1925	37.66±2.93	5.54±0.91	31.73±2.66
6. MNU+1 × 7-day cycle 1% λCgN	10	27 715±1715	46.54±5.63	6.76±1.10	38.60±5.18
7. MNU+1 × 7-day cycle 4% λCgN	10	32 539±1543	52.31±4.82	9.61±0.78	39.39±4.72
8. MNU+3 × 7-day cycles 1% λCgN	10	30 651±2091	59.85±6.91	8.27±1.56	51.46±6.81
9. MNU+3 × 7-day cycles 4% λCgN	10	30 640±3176	52.47±7.80	9.62±0.67	43.79±5.89
10. MNU+continuous 1% λCgN	10	31 372±1832	47.86±5.96	8.00±1.14	38.14±5.11
11. MNU+continuous 4% λCgN	10	23 450±1007	56.23±5.41	5.82±0.69	49.98±5.09

MTCRII=metallothionein crypt-restricted immunopositivity indices; MT=metallothionein; DMSO=dimethylsulphoxide; λCgN=lambda carrageenan; MNU=N-methyl-N-nitrosourea.