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. 2005 May 31;92(12):2160–2165. doi: 10.1038/sj.bjc.6602633

Table 3. Treatment effects upon number and size of ACF.

Group Treatment Mice (n) No. of ACF per colon No. of ACF per 104 crypts No. of aberrant crypts per ACF
 1 Water only 5 0.40±0.24 0.09±0.04 0.60±0.28
 2 DMSO only 5 0.20±0.20 0.07±0.04 0.40±0.25
 3 Continuous 1% λCgN 5 0.80±0.20 0.21±0.04 1.60±0.34
 4 Continuous 4% λCgN 5 1.00±0 0.25±0.005 2.40±0.24
 5 MNU only 10 3.90±0.23 1.37±0.015 4.00±0.17
 6 MNU+1 × 7-day cycle 1% λCgN 10 5.00±0.29 1.67±0.18 4.00±0.16
 7 MNU+1 × 7-day cycle 4% λCgN 10 4.90±0.23 1.56±0.14 5.90±0.21
 8 MNU+3 × 7-day cycle 1% λCgN 10 5.80±0.24 2.04±0.14 6.58±0.33
 9 MNU+3 × 7-day cycle 4% λCgN 10 6.70±0.21 2.52±0.39 5.80±0.17
10 MNU+continuous 1% λCgN 10 5.00±0.25 1.65±0.14 5.90±0.22
11 MNU+continuous 4% λCgN 10 6.80±0.29 2.95±0.21 5.38±0.26

ACF=aberrant crypt foci; DMSO=dimethylsulphoxide; λCgN= lambda carrageenan; MNU=N-methyl-N-nitrosourea.