Figure 2.

An active siRNA inhibiting hWAPL expression suppressed the growth of subcutaneous tumours derived from SiHa cells inoculated into nude mice. (A) Tumour growth curves. The tumour volume (mm³) was approximated by multiplication of the major axis, the minor axis, and the height of each tumour. Each data point represents the mean of eight samples. Bars, s.e. (B) Weights of the tumours in nude mice 25 days after the first siRNA injection. Each data point represents the mean of eight samples. Bars, s.e. ^*P<0.001 vs negative control. ^**P<0.001 vs no treatment. (C) Representative histology of the subcutaneous tumours in nude mice. The excised tumours were subjected to paraffin sectioning, then stained with haematoxylin and eosin.