Table 2. Relationship between Snail mRNA expression and clinicopathologic features.
|
Snail mRNA expression
|
|||
|---|---|---|---|
| Factors | N | (Mean±s.d.) | P-value |
| Gender | |||
| Male | 33 | 0.841±2.084 | |
| Female | 14 | 1.132±2.170 | 0.668 |
| Age (years) | |||
| ⩽65 | 19 | 1.128±2.720 | |
| >65 | 28 | 0.792±1.570 | 0.594 |
| Liver cirrhosis | |||
| Absent | 23 | 0.862±1.718 | |
| Present | 24 | 0.991±2.430 | 0.835 |
| Alpha-fetoprotein (ng ml−1) | |||
| ⩽10 | 12 | 0.578±0.488 | |
| >10 | 35 | 1.047±2.403 | 0.508 |
| Tumour multiplicity | |||
| Solitary | 28 | 0.556±0.517 | |
| Multiple | 19 | 1.476±3.199 | 0.140 |
| Tumour size (mm) | |||
| ⩽50 | 33 | 0.792±2.084 | |
| >50 | 14 | 1.248±2.147 | 0.500 |
| Histological grade | |||
| Well | 21 | 1.165±2.582 | |
| Moderate | 26 | 0.736±1.619 | 0.490 |
| Capsular invasion (fc-inf) | |||
| Absent | 14 | 0.281±0.268 | |
| Present | 31 | 1.258±2.516 | 0.157 |
| Portal vein invasion (vp) | |||
| Absent | 35 | 0.556±0.486 | |
| Present | 12 | 2.011±3.978 | 0.035 |
| Hepatic vein invasion (vv) | |||
| Absent | 36 | 0.751±1.403 | |
| Present | 11 | 1.506±3.568 | 0.299 |
| Intrahepatic metastasis (im) | |||
| Absent | 32 | 0.535±0.509 | 0.050 |
| Present | 15 | 1.765±3.561 | |
Well=well-differentiated HCC, Moderate=moderately differentiated HCC, fc-inf, vp, vv, im, diagnosed by pathological findings.