Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2005 Feb 8;92(4):784–790. doi: 10.1038/sj.bjc.6602381

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2005 Cancer Research UK

This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material.If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

The 1100delC mRNA transcript is present in mutant LCLs at a reduced level compared to wild-type CHEK2. (A) cDNA sequence electrograms of the PCR products with arrows showing the position of 1100delC variation in heterozygous LCLs. Sequences are presented in the 5′–3′ direction. (B) Autoradiograph of SnuPE reactions from wild-type and heterozygous LCLs with both forward and reverse primers. (C) Quantitation of 1100delC expression in the three heterozygous LCLs. The mean of the duplicates was calculated and the level of the 1100delC mRNA was expressed as a ratio of the variant compared to wild type in both the forward and reverse directions.