Table 4. Correlation analysis of genomic aberrations in human HCCs (in ⩾20%; n=498).
| Chromosome | 1q (gain) | 4q (loss) | 6p (gain) | 8p (loss) | 8q (gain) | 13q (loss) | 16q (loss) | 17p (loss) | 17q (gain) |
|---|---|---|---|---|---|---|---|---|---|
| 1q | |||||||||
| gain | — | 43 | 30.6 | 45.7 | 52.6 | 30.2 | 38.1 | 36.8 | — |
| Ø | — | 19.8 | 11.1 | 25.6 | 30.4 | 16.4 | 23.7 | 21.3 | — |
| 4q | |||||||||
| Loss | 73.4 | — | — | 51.6 | — | 42 | 53.2 | 41 | 29.8 |
| Ø | 41.9 | — | — | 28.7 | — | 13.9 | 19.4 | 23.9 | 15.5 |
| 6p | |||||||||
| Gain | 76.9 | — | — | 52.1 | — | — | — | — | — |
| Ø | 45.9 | — | — | 32.6 | — | — | — | — | — |
| 8p | |||||||||
| Loss | 66.3 | 46.6 | 33.7 | — | — | — | 48.3 | 41 | — |
| Ø | 46.6 | 26.3 | 17.2 | — | — | — | 23.1 | 24.4 | — |
| 8q | |||||||||
| Gain | 65.5 | — | — | — | — | — | — | — | — |
| Ø | 43.5 | — | — | — | — | — | — | — | — |
| 13q | |||||||||
| Loss | 68.7 | 57.3 | — | — | — | — | 52.7 | — | — |
| Ø | 48.2 | 25.3 | — | — | — | — | 24.8 | — | — |
| 16q | |||||||||
| Loss | 65 | 56.4 | — | 55.2 | — | 41.1 | — | 42.9 | — |
| Ø | 47.8 | 22.4 | — | 28.7 | — | 16.4 | — | 24.2 | — |
| 17p | |||||||||
| Loss | 66.9 | 44.8 | — | 51.3 | — | — | 46.8 | — | — |
| Ø | 48.8 | 28.5 | — | 31.1 | — | — | 25.6 | — | — |
| 17q | |||||||||
| Gain | — | 55 | — | — | — | — | — | — | — |
| Ø | — | 28.2 | — | — | — | — | — | — | — |
Only significant differences between distinct chromosomal imbalances (first line) and the possibles status of all other high-frequency alterations (gain/loss vs no changes) are shown (P<0.05).