Table 2. BRCA1 and BRCA2 mutation status of the cases and controls.
| All women (n=258) | Controls (n=252) | Cases (n=6) | |
|---|---|---|---|
| No. (%) | No. (%) | No.(%) | |
| BRCA1 | |||
| Positive | 20 (7.8%) | 16 (6.3%) | 4 (80.0%) |
| Negative | 47 (18.2%) | 47 (18.7%) | — |
| Untested | 17 (6.6%) | 17 (6.7%) | — |
| BRCA2 | |||
| Positive | 7 (2.7%) | 7 (2.8%) | — |
| Negative | 6 (2.3%) | 6 (2.4%) | — |
| Untested | 2 (0.8%) | 2 (0.8%) | — |
| Non-BRCA1/2 family | 113 (43.8%) | 113 (44.8%) | — |
| Untested family | 46 (17.8%) | 44 (17.5%) | 2 (20.0%) |
We considered women who belong to known BRCA1 or BRCA2 families to be non-mutation carriers if they tested negative themselves or if their parent tested negative for the known mutation in the family. Untested women from BRCA1 and BRCA2 families have between 25 and 50% risk of carrying the mutation segregating in their respective families.