Table 1. Characteristics of the case-control material.
Single smear cohort
|
Random smear cohort
|
|||
---|---|---|---|---|
Cases | Controls | Cases | Controls | |
n | 62 | 501 | 139 | 548 |
Year of birth | ||||
Mean | 1946.8 | 1949.0 | 1946.6 | 1949.0 |
Range | 1922–1965 | 1922–1968 | 1922–1968 | 1922–1968 |
Age at smear collection | ||||
Mean | 34.7 | 30.9 | 34.6 | 29.8 |
Range | 20–62 | 15–63 | 15–62 | 15–63 |
Human DNA | ||||
Meana | 159.8 | 219.2 | 175.7 | 206.2 |
Range | 5.0–1354 | 5.4–6264 | 5.0–2465 | 5.0–15914 |
HPV 16 | ||||
No of positive women | 28 | 28 | 87 | 56 |
No of positive smears | 28 | 28 | 120 | 66 |
Mean viral loadb | 138.3 | 17.7 | 97.0 | 12.9 |
Range | 0.05–2812 | 0.02–300.3 | 0.03–2812 | 0.01–300.3 |
HPV 31 | ||||
No of positive women | 5 | 19 | 9 | 34 |
No of positive smears | 5 | 19 | 15 | 39 |
Mean viral loadb | 17.7 | 37.4 | 29.8 | 50.5 |
Range | 0.50–36.7 | 0.03–543.1 | 0.3–147.2 | 0.02–762.6 |
HPV 18/45 | ||||
No of positive women | 8 | 28 | 28 | 55 |
No of positive smears | 8 | 28 | 39 | 64 |
Mean viral loadb | 157.6 | 77.2 | 265.3 | 71.4 |
Range | 0.11–1158 | 0.01–1402 | 0.02–5105 | 0.01–2044 |
Mean estimated number of human cells equivalents per reaction.
Mean number of HPV genomes per human cell equivalent.