Table 3. Genes commonly upregulated and downregulated in gastric cancers.
| Accession IDa | Gene name | Normal | Tumour | MFCb | P c |
|---|---|---|---|---|---|
| Upregulated genes | |||||
| AB000712 | CPE-receptor | 221.50 | 2204.38 | 9.95 | 2.10E-06 |
| M18728 | Nonspecific crossreacting antigen | 241.22 | 2275.94 | 9.44 | 5.40E-03 |
| M29540 | Carcinoembryonic antigen | 262.13 | 2364.40 | 9.02 | 1.66E-03 |
| AJ238246 | Sarcolectin | 82.90 | 726.15 | 8.76 | 2.82E-03 |
| D78611 | MEST | 45.57 | 399.95 | 8.76 | 2.67E-03 |
| U04313 | Maspin | 226.72 | 1693.48 | 7.47 | 9.47E-04 |
| L17131 | High mobility group protein (HMG-I(Y)) | 307.70 | 1933.66 | 6.28 | 1.16E-05 |
| AL031983 | dJ271M21.6 (Diubiquitin) | 286.75 | 1741.25 | 6.07 | 2.39E-03 |
| AA156240 | Homo sapiens cDNA | 280.58 | 1691.72 | 6.03 | 1.82E-04 |
| J03464 | Collagen alpha-2 type I | 518.23 | 2991.88 | 5.77 | 1.67E-03 |
| X54942 | ckshs2 | 170.18 | 968.87 | 5.69 | 1.76E-05 |
| U73379 | Cyclin-selective ubiquitin carrier protein | 283.25 | 1525.39 | 5.39 | 1.66E-06 |
| AA976838 | oq35c12.s1 Homo sapiens cDNA | 155.18 | 835.00 | 5.38 | 5.84E-03 |
| J04088 | DNA topoisomerase II (Top2) | 208.87 | 1092.85 | 5.23 | 9.23E-03 |
| D80008 | KIAA0186 | 73.47 | 364.53 | 4.96 | 1.28E-03 |
| AA203476 | zx55e01.r1 Homo sapiens cDNA | 131.52 | 646.47 | 4.92 | 2.77E-07 |
| U55206 | Gamma-glutamyl hydrolase (hGH) | 74.68 | 327.58 | 4.39 | 6.20E-04 |
| J04152 | Gastrointestinal tumour-associated | 483.73 | 2028.00 | 4.19 | 1.51E-05 |
| Antigen GA733-1 protein | |||||
| U97188 | Putative RNA-binding protein KOC | 58.85 | 246.36 | 4.19 | 2.35E-04 |
| D11139 | Tissue inhibitor of | 1047.67 | 4334.40 | 4.14 | 5.03E-03 |
| metalloproteinases | |||||
| U28386 | Nuclear localisation sequence | 122.48 | 505.54 | 4.13 | 1.65E-06 |
| receptor hSRP1 alpha | |||||
| U97669 | Notch3 | 123.62 | 510.09 | 4.13 | 4.11E-04 |
| AB000714 | hRVP1 | 194.80 | 788.65 | 4.05 | 4.22E-03 |
| Downregulated genes | |||||
| AB020629 | KIAA0822 | 204.94 | 48.96 | 0.24 | 3.00E-4 |
| AL050159 | DKFZp586A0522 | 1940.37 | 434.71 | 0.224 | 1.89E-3 |
a
Gene bank accession ID.
b
MFC, median fold change; tumour vs normal mucosa (T/N) gene expression values.
c
Calculated by Mann–Whitney’s U-test.