Table 2. Studies included in the present meta-analysis.
| Authors | Study design | Stage | No. of limited resection | No. of lobectomy | Reasons for limited resection | Survival difference |
|---|---|---|---|---|---|---|
| Hoffmann and Ransdell (1980) | RS | IA | 33 (W) | 40a | Poor cardiopulmonary function and smaller lesions | NS |
| Read et al (1990) | RS | IA | 113 (1O7S+6W) | 131 | ND | NS (CSS) |
| Date et al (1994) | MPS | IA | 16 (6S+10W) | 16 | Poor pulmonary function | Lobectomy better |
| Warren and Faber (1994) | RS | IA+B | 66 (S) | 103 | Poor cardiopulmonary function and smaller lesions | Lobectomy better |
| Harpole et al (1995) | RS | IA+B | 75 (W) | 193 | Poor cardiopulmonary function and smaller lesions | NS (CSS) |
| LCSG (1996) | RCT | IA | 122 (82S+40W) | 125 | Randomisation | NS |
| Kodama et al (1997) | RS | IA | 46b (W) | 77 | Intentional resection for small lesions | NS |
| Landreneau et al (1997) | RS | IA | 102 (W) | 117 | Poor cardiopulmonary function | NS |
| Pastorino et al (1997) | RS | IA+B | 53 (S+W) | 367 | ND | NS |
| Kwiatkowski et al (1998) | RS | IA+B | 58 (S+W) | 186c | ND | Lobectomy better |
| Okada et al (2001) | RS | IA⩽2 cm | 70 (S) | 139 | Intentional resection for small lesions ⩽2 cm | NS |
| Koike et al (2003) | RS | IA⩽2 cm | 74 (60S+14W) | 159 | Intentional resection for small lesions ⩽2 cm | NS |
| Campione et al (2004) | RS | IA | 21 (S) | 100 | Poor cardiopulmonary function | NS |
| Keenan et al (2004) | RS | IA+B | 54 (8) | 147 | Poor pulmonary function | NS |
a
Tumours peripherally located.
b
Only intentional resection.
c
Including 13 pneumonectomies.
LCSG=Lung Cancer Study Group; S=segmentectomy; W=wedge resection; ND=not described; NS=not significant; MPS=matched-pair study; RCT=randomised controlled trial; RS=retrospective study; CSS=cancer-specific survival.