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. 2005 Mar 15;92(6):1069–1077. doi: 10.1038/sj.bjc.6602470

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Copyright © 2005 Cancer Research UK

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Immune effector function of mAb 806 (○), chimeric IgGl antibody ch806 (•) and Isotype control cG250 (▾). (A) Complement-dependent cytotoxicity activity of 0–10 μg ml⁻¹ antibody on target U87MG.de2-7 cells. Antibody-dependent cellular cytotoxity on target (B) A431 cells and (C) U87MG.de2-7 cells at effector-to-target cell ratio of 50 : 1 and antibody concentrations ranging from 0 to 10 μg ml⁻¹. Mean (bars;±s.d.) percent cytotoxicity of triplicate determinations are presented. Representative results from three separate experiments are shown.