Table 4. Presence or absence of lung cancer in relatives of probands and relatives of spouses.
Relative | Lung cancer presence | Proband | Spouse | OR1a | 95% CI | OR2b | 95% CI |
---|---|---|---|---|---|---|---|
Father | Yes | 43 | 20 | 2.22* | 1.26–3.95 | 2.17** | 1.21–3.86 |
No | 697 | 720 | |||||
Mother | Yes | 50 | 15 | 3.50* | 1.89–6.58 | 3.78* | 2.03–7.12 |
No | 690 | 725 | |||||
Parent | Yes | 93 | 35 | 2.77* | 1.83–4.19 | 2.90* | 1.97–4.32 |
No | 1387 | 1445 | |||||
Brother | Yes | 61 | 47 | 1.23 | 0.82–1.86 | 1.21 | 0.79–1.80 |
No | 935 | 889 | |||||
Sister | Yes | 55 | 27 | 2.07* | 1.26–3.42 | 2.23* | 1.46–4.00 |
No | 581 | 591 | |||||
Sibling | Yes | 116 | 74 | 1.53* | 1.12–2.09 | 1.65** | 1.19–2.18 |
No | 1516 | 1480 | |||||
Malec | Yes | 104 | 67 | 1.53* | 1.10–2.12 | 1.33** | 1.02–2.02 |
No | 1632 | 1609 | |||||
Female | Yes | 105 | 42 | 2.59* | 1.77–3.80 | 2.67* | 1.90–3.94 |
No | 1271 | 1316 | |||||
Total | Yes | 209 | 109 | 1.93* | 1.51–2.47 | 2.05* | 1.68–2.53 |
No | 2903 | 2925 |
OR=odds ratio; CI=confidence interval.
P<0.01.
P<0.05.
OR1, estimate of lung cancer for relatives of probands vs relatives of spouses, not adjusted.
OR2, estimate of lung cancer for relatives of probands vs relatives of spouses, adjusted for age, sex, birth order, size of the family, commune of residence, COPD, smoking and cumulation index of smoky coal exposure.
Fathers and brothers.