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. 2005 Mar 8;92(7):1321–1325. doi: 10.1038/sj.bjc.6602465

Table 4. Presence or absence of lung cancer in relatives of probands and relatives of spouses.

Relative Lung cancer presence Proband Spouse OR1a 95% CI OR2b 95% CI
Father Yes 43 20 2.22* 1.26–3.95 2.17** 1.21–3.86
  No 697 720        
Mother Yes 50 15 3.50* 1.89–6.58 3.78* 2.03–7.12
  No 690 725        
Parent Yes 93 35 2.77* 1.83–4.19 2.90* 1.97–4.32
  No 1387 1445        
Brother Yes 61 47 1.23 0.82–1.86 1.21 0.79–1.80
  No 935 889        
Sister Yes 55 27 2.07* 1.26–3.42 2.23* 1.46–4.00
  No 581 591        
Sibling Yes 116 74 1.53* 1.12–2.09 1.65** 1.19–2.18
  No 1516 1480        
Malec Yes 104 67 1.53* 1.10–2.12 1.33** 1.02–2.02
  No 1632 1609        
Female Yes 105 42 2.59* 1.77–3.80 2.67* 1.90–3.94
  No 1271 1316        
Total Yes 209 109 1.93* 1.51–2.47 2.05* 1.68–2.53
  No 2903 2925        

OR=odds ratio; CI=confidence interval.

*

P<0.01.

**

P<0.05.

a

OR1, estimate of lung cancer for relatives of probands vs relatives of spouses, not adjusted.

b

OR2, estimate of lung cancer for relatives of probands vs relatives of spouses, adjusted for age, sex, birth order, size of the family, commune of residence, COPD, smoking and cumulation index of smoky coal exposure.

c

Fathers and brothers.